Table 4 Power of genotype association statistics given as 1-β error probability. The β represents the probability of falsely accepting H0 hypothesis (lack of association) when in fact H1 hypothesis (association) is true.
Polymorphism | Genet. model | CD | PSC | PBC |
|---|---|---|---|---|
NOD2/CARD15 Pro268Ser | dominant | 0.59 | 0.04 | <0.01 |
| Â | recessive | 0.98 | 0.03 | 0.04 |
NOD2/CARD15 Arg702Trp | dominant | 0.71 | 0.11 | 0.08 |
| Â | recessive | n/a | <0.01 | n/a |
NOD2/CARD15 Gly908Arg | dominant | <0.01 | <0.01 | 0.05 |
| Â | recessive | n/a | n/a | n/a |
NOD2/CARD15 1007fs | dominant | 0.99 | 0.02 | 0.01 |
| Â | recessive | 0.86 | <0.01 | n/a |
OCTN1 Leu503Phe | dominant | 0.08 | <0.01 | <0.01 |
| Â | recessive | 0.04 | 0.02 | 0.02 |
OCTN2-207G>C | dominant | <0.01 | <0.01 | 0.01 |
| Â | recessive | <0.01 | 0.09 | <0.01 |
DLG5 Arg30Gln | dominant | <0.01 | 0.02 | 0.01 |
| Â | recessive | <0.01 | 0.02 | <0.01 |
IL23R Arg381Gln | dominant | <0.01 | 0.08 | 0.03 |
| Â | recessive | <0.01 | <0.01 | n/a |
IL23R His3Gln | dominant | 0.09 | 0.01 | 0.06 |
| Â | recessive | <0.01 | 0.02 | <0.01 |
IL23R exon-3'UTR | dominant | 0.05 | 0.01 | 0.01 |
| Â | recessive | <0.01 | 0.01 | <0.01 |
ATG16L1 Thr300Ala | dominant | 0.32 | 0.04 | 0.01 |
| Â | recessive | 0.05 | 0.04 | 0.02 |