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Table 3 HLA-DQB1 distribution in Mexican Mestizo DQB1*0602 negative patients and controls.

From: Association of narcolepsy-cataplexy with HLA-DRB1 and DQB1in Mexican patients: A relationship between HLA and gender is suggested

Locus

Patients

Controls

     

DQB1*

ΛN = 11

AF%

Ï‚N = 181

AF%

X2Y

OR

(CI)

p

pc

0201

4

18.2

38

10.5

0.6

    

0301

11**

50

97

26.8

4.4

2.7

(1.1–6.5)

0.035

NS

0302

3

13.6

104

28.7

1.7

    

0303

0

0

5

1.4

0.2

    

0402

2

9.1

55

15.2

0.2

    

0501

1

4.5

33

9.1

0.1

    

0502

0

0

5

1.4

0.2

    

0503

0

0

5

1.4

0.2

    

0601

0

0

4

1.1

0.3

    

0603

0

0

7

1.9

0

    

0604

0

0

7

1.9

0

    

0605

1

4.5

1

0.3

1.4

    

0609

0

0

1

0.3

1.4

    
  1. AF: allele frequency; X2Y: Chi2 value with Yates correction; OR: Odds Ratio; CI: Confidence Interval; pc: Bonferroni correction (the p value was multiplied by the total number of alleles tested); NS: Not significant; Λ: 11/32 total patients were DQB1*0602 negative; ς: 181/203 total controls were DQB1*0602 negative. ** this number includes two DQB1*0301 homozygotes.
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BMC Medical Genetics

ISSN: 1471-2350

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