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Table 3 Logistic GEE results incorporating both polymorphisms

From: Polymorphisms near EXOC4 and LRGUK on chromosome 7q32 are associated with Type 2 Diabetes and fasting glucose; The NHLBI Family Heart Study

Diabetes Status

 

Homozygous deletion

rs7903146 minor allele

 

OR [95% CI]

p-value

OR [95% CI]

p-value

Both sexes

0.47 [0.25,0.87]

0.016

1.31 [0.95,1.81]

0.099

Women

0.57 [0.22,1.52]

0.26

1.63 [1.02,2.59]

0.039

Men

0.45 [0.20,1.05]

0.064

1.14 [0.76, 1.72]

0.53

  1. Results from logistic GEE models incorporating the deletion genotyping and rs7903146, including sex-stratified results. Odds ratios (OR), 95% confidence interval (95% CI) and p-values are reported.
  2. *205 cases, 1982 controls – adjusted for BMI at age25, onset age for cases (w/square and cubed)
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BMC Medical Genetics

ISSN: 1471-2350

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