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Table 3 Up/down regulated genes in PBMC lacking ARHGAP4

From: Immunological profile in a family with nephrogenic diabetes insipidus with a novel 11 kb deletion in AVPR2 and ARHGAP4 genes

Gene Name Description aFold change b q value cAccession
Up-regulation
PLK3 Polo-like kinase 3 4.35 0.0402 NM_004073
NHSL2 NHS-like 2 2.38 0.0453 NM_001013627
PTAFR Platelet-activating factor receptor 2.27 0.0288 NM_000952
KLHL26 Kelch-like 26 1.99 0.0272 NM_018316
MAPKAPK2 Mitogen-activated protein kinase- activated protein kinase 2 1.96 0.0442 NM_032960
CKAP4 Cytoskeleton-associated protein 4 1.85 0.0272 NM_006825
CYB5R3 Cytochrome b5 reductase 3 1.82 0.0328 NM_007326
ZC3H12A Zinc finger CCCH-type containing 1.81 0.0428 NM_025079
FURIN Furin 1.79 0.0448 NM_002569
GRN Granulin 1.76 0.0453 NM 002087
PPOX Protoporphyrinogen oxidase 1.75 0.0307 NM_000309
NQO2 NAD(P)H dehydrogenase, quinone 2 1.74 0.0453 NM_000904
DPH3 Diphthamide biosynthesis protein 3 1.70 0.0307 NM_206831
PGD Phosphogluconate dehydrogenase 1.68 0.00562 NM_002631
RIPK5 Receptor interacting protein kinase 5 1.66 0.0386 NM_015375
CD14 CD14 molecule 1.62 0.0272 NM_000591
PGD Phosphogluconate dehydrogenase 1.57 0.0272 NM_002631
Down-regulation     
TUSC4 Tumor suppressor candidate 4 0.63 0.0453 NM_006545
PLEKHG4 Pleckstrin homology domain containing, family G (with RhoGef 0.62 0.0272 NM_015432
SFXN1 Sideroflexin 1 0.61 0.0272 NM_022754
GNRH1 Gonadotropin-releasing hormone 1 0.60 0.0328 NM_000825
PPP1R3E Protein phosphatase 1, regulatory 0.60 0.0383 XM_940069
MC1R Melanocortin 1 receptor 0.56 0.0272 NM_002386
LRCH4 Leucine-rich repeats and calponin homology (CH) domain containing 4 0.55 0.0411 NM_002319
LOC642787 Hypothetical protein LOC642787 0.44 0.0288 XM_926202
SGPP2 Sphingosine-1-phosphate phosphotase 0.09 0.0307 XM_938742
BNIPL BCL2/adenovirus E1B 19 kD 0.06 0.0226 NM_138278
ARHGAP4 Rho GTPase activating protein 4 0.00 0.000567 NM_001666
  1. aThe fold change was determined by calculating the ratio of global normalized signals from the PBMCs of NDI patients to those from the PBMCs of normal subjects. bP values corrected by the Benjamini and Hochberg false discovery rate, and expressed as q values cGenBank accession numbers