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Table 6 Threshold to obtain 90% sensitivity and corresponding specificity

From: Selecting a BRCA risk assessment model for use in a familial cancer clinic

Model Threshold to obtain 90% sensitivity Specificity at 90% sensitivity
  All Low risk subset High risk subset All Low risk subset High risk subset
BRCA status       
BRCAPRO 1.97 0.47 4.20 0.21 0.06 0.39
Manchester 7.58 7.60 7.10 0.27 0.17 0.31
Penn II 10.90 10.65 11.20 0.35 0.18 0.45
Myriad II 5.80 6.20 5.75 0.36 0.27 0.40
FHAT 6.00 4.10 8.83 0.26 0.26 0.38
IBIS 0.26 - - 0.18 - -
BOADICEA 2.77 1.94 3.08 0.22 0.11 0.25