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Table 5 Sensitivity and specificity at the conventional thresholds

From: Selecting a BRCA risk assessment model for use in a familial cancer clinic

Model Conventional threshold Sensitivity at conventional threshold Specificity at conventional threshold
   All Low risk subset High risk subset All Low risk subset High risk subset
BRCA status        
BRCAPRO 10 0.75 0.63 0.82 0.62 0.70 0.58
Manchester 15 0.58 0.39 0.64 0.71 0.73 0.72
Penn II 10 0.93 0.94 0.92 0.31 0.14 0.40
Myriad II 10 0.71 0.66 0.74 0.63 0.65 0.62
FHAT 10 0.70 0.34 0.89 0.63 0.85 0.51
IBIS 10 0.20 - - 0.74 - -
BOADICEA 10 0.70 0.63 0.74 0.65 0.70 0.62