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Table 2 Gender and age distribution of the PTPN22 C1858T polymorphism in Spanish T1D patients

From: Susceptibility to type 1 diabetes conferred by the PTPN22C1858T polymorphism in the Spanish population

 

Genotypes (%)

T1D vs. Controls (carrier of T vs CC)

Subjects

CC

CT

TT

OR CI (95%)

p

Female T1D ≤ 15 (n = 70)

49 (70.0)

19 (27.1)

2 (2.9)

2.92 (1.59–5.33)

0.0001

Male T1D ≤ 15 (n = 71)

61 (85.9)

10 (14.1)

0

1.12 (0.51–2.37)

0.76

Female T1D > 15 (n = 70)

56 (80.0)

12 (17.1)

2 (2.9)

1.70 (0.85–3.34)

0.10

Male T1D > 15 (n = 70)

56 (80.0)

13 (18.6)

1 (1.4)

1.70 (0.85–3.34)

0.10

Controls

483 (87.2)

68 (12.3)

3 (0.5)

  
  1. Female T1D ≤ 15 vs. Male T1D ≤ 15:
  2. (TT+CT) vs. CC; OR (95%) = 2.61 (1.05–6.62); p = 0.022