Skip to main content

Table 1 Analysis of the PTPN22 C1858T variant in the Spanish cohort

From: Susceptibility to type 1 diabetes conferred by the PTPN22C1858T polymorphism in the Spanish population

 

Genotypes (%)

Alleles (%)

Subjects

CC

CT

TT

C

T

Controls (n = 554)

483 (87.2)

68 (12.3)

3 (0.5)

1034 (93.3)

74 (6.7)

   Female (n = 197)

172 (87.3)

23 (11.7)

2 (1.0)

367 (93.1)

27 (6.9)

   Male (n = 189)

168 (89.9)

20 (10.6)

1 (0.5)

356 (94.2)

22 (5.8)

Cases (n = 316)

252 (79.7)

59 (18.7)

5 (1.6)

563 (89.1)

69 (10.9)

   Female (n = 159)

122 (76.7)

33 (20.8)

4 (2.5)

277 (87.1)

41 (12.9)

   Male (n = 157)

130 (82.8)

26 (16.1)

1 (0.6)

286 (91.1)

28 (8.9)

  1. Patients vs. controls:
  2. T vs. C; OR (95%) = 1.71 (1.20–2.45); p = 0.002
  3. (TT+CT) vs. CC; OR (95%) = 1.73 (1.17–2.54); p = 0.004