Table 4 Associations between haplotypes and spina bifida risk, non-Hispanic White vs. Hispanic White
From: Association between CFL1gene polymorphisms and spina bifida risk in a California population
Haplotype | Freq. (95% CI) § | Estimated Haplotype Counts | OR | 95% CI | |
|---|---|---|---|---|---|
| Â | Â | Case | Control | Â | Â |
Non-Hispanic White | Â | Â | Â | Â | Â |
TAACG | 0.642 (0.588,0.695) | 96.7 | 192.5 | ref. | Â |
CGGTT | 0.161 (0.123,0.206) | 38.7 | 48.4 | 1.6 | 0.9, 2.6 |
CGATT | 0.128 (0.094,0.169) | 24.1 | 38.3 | 1.3 | 0.7, 2.2 |
CGATG | 0.028 (0.009,0.075) | 8.3 | 3.2 | -- | -- |
TAACT | 0.024 (0.011,0.047) | 1.1 | 7.3 | -- | -- |
Hispanic White | Â | Â | Â | Â | Â |
CGATT | 0.441 (0.376,0.505) | 108.7 | 98.7 | ref. | Â |
TAACG | 0.414 (0.354,0.483) | 96.9 | 92.8 | 0.9 | 0.6, 1.4 |
CGGTT | 0.108 (0.073,0.155) | 43.2 | 24.2 | 1.6 | 0.9, 2.9 |
TAACT | 0.023 (0.010,0.051) | 3.1 | 5.2 | -- | -- |
Non-Hispanic White | Â | Â | Â | Â | Â |
Block 1 | rs652021-rs4621 | Â | Â | Â | Â |
TA | 0.683 (0.629,0.733) | 99.0 | 209.0 | ref. | Â |
CG | 0.314 (0.264,0.368) | 68.0 | 96.0 | 1.5 | 1.0, 2.2 |
Block 2 | rs11227332-rs665306 | Â | Â | Â | Â |
AC | 0.668 (0.614,0.720) | 100.6 | 201.7 | ref. | Â |
AT | 0.162 (0.124,0.207) | 27.2 | 48.3 | 1.1 | 0.7, 1.9 |
GT | 0.165 (0.129,0.213) | 41.0 | 50.4 | 1.6 | 1.0, 2.6 |
Hispanic White | Â | Â | Â | Â | Â |
Block 1 | rs652021-rs4621 | Â | Â | Â | Â |
TA | 0.442 (0.379,0.508) | 100.0 | 100.0 | ref. | Â |
CG | 0.553 (0.488,0.617) | 153.0 | 125.0 | 1.2 | 0.9,1.8 |
Block 2 | rs11227332-rs665306 | Â | Â | Â | Â |
AT | 0.456 (0.394,0.523) | 112.1 | 102.6 | ref. | Â |
AC | 0.438 (0.375,0.503) | 100.5 | 99.0 | 0.9 | 0.6, 1.4 |
GT | 0.106 (0.074,0.156) | 43.4 | 24.4 | 1.6 | 0.9, 2.9 |