Skip to main content

Table 2 Common haplotype and minor allele frequencies for SNPs within haplotype blocks in unaffected parents (n = 350–650 individuals), determined by individual genotyping.

From: An investigation of polymorphisms in the 17q11.2-12 CC chemokine gene cluster for association with multiple sclerosis in Australians

(a) 5' block

CCL2 -2581A>G

CCL2 -2138A>T

CCL11 -488C>A

CCL11 67G>A

Haplotype Frequency

Haplotypes

    

A

A

C

G

0.33

G

A

C

G

0.29

A

A

A

A

0.19

A

T

C

G

0.18

Minor allele frequency

    

G

T

A

A

 

0.29

0.19

0.19

0.20

 

(b) 3' block

    

CCL14 -649T>A

CCL15 -1284A>C

CCL23 316T>C

CCL23 -289A>C

Haplotype Frequency

Haplotypes

    

T

A

T

A

0.76

A

A

C

C

0.12

A

C

C

C

0.07

Minor allele frequency

    

A

C

C

C

 

0.23

0.08

0.20

0.20

 

(c) Minor allele frequencies of remaining SNPs

    

SNP

Minor allele frequency

   

CCL8 -572C>T

T 0.37

   

CCL5 -471C>T

T 0.19

   

CCL16 -595C>A

A 0.22

   

CCL15 136+88C>T

T 0.05

   
Back to article page

BMC Medical Genetics

ISSN: 1471-2350

Contact us