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Table 3 Allele frequencies in non-carriers or French Canadians unaffected with cancer and carriers of 3398delAAAAG mutation.

From: Haplotype analysis suggest common founders in carriers of the recurrent BRCA2mutation, 3398delAAAAG, in French Canadian hereditary breast and/ovarian cancer families

Allele

Marker (number of subjects)

 

D13S260

D13S1699

D13S1698

D13S1697

D13S1701

D13S171

 

NC (45)

C (11)

NC (43)

C (11)

NC (51)

C (11)

NC (35)

C (11)

NC (41)

C (11)

NC (41)

C (11)

0

-

-

-

-

-

-

-

-

-

-

-

-

1

-

-

0.05

0.05

-

-

0.01

0.05

0.01

-

0.02

-

2

0.02

-

0.02

-

0.02

-

0.74

0.41

0.07

0.14

0.40

0.27

3

0.19

0.05

0.62

0.59

0.05

0.09

0.24

0.55

0.22

0.23

0.02

-

4

0.08

0.09

0.27

0.32

0.03

-

-

-

0.23

0.50

-

-

5

0.09

0.05

0.02

-

0.02

-

-

-

0.18

0.05

0.01

0.05

6

0.06

-

0.01

0.05

0.08

0.05

-

-

0.21

0.09

-

-

7

0.32

0.73

-

-

0.04

-

-

-

0.06

-

0.33

0.55

8

0.11

0.05

-

-

0.02

0.05

-

-

-

-

-

-

9

0.12

0.05

-

-

0.40

0.68

-

-

0.01

-

0.21

0.14

10

0.01

-

-

-

0.04

-

-

-

-

-

-

-

11

-

-

0.01

-

0.30

0.14

-

-

-

-

-

-

12

-

-

-

-

-

-

-

-

-

-

-

-

13

-

-

-

-

-

-

-

-

-

-

-

-

  1. The figures in bold type show the most common allele. Alleles in italics associated with 3398delAAAAG mutation. NC and C refer to non-carriers and carriers of this mutation, respectively.
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BMC Medical Genetics

ISSN: 1471-2350

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