Skip to main content

Table 1 General characterization of C282Y homozygous probands at the time of diagnosis according to gender

From: A study of 82 extended HLA haplotypes in HFE-C282Y homozygous hemochromatosis subjects: relationship to the genetic control of CD8+ T-lymphocyte numbers and severity of iron overload

 

Males n = 32

Females n = 11

p*

Age (years)

51 ± 13 (29–75)

47 ± 11 (32–65)

n.s.

Transferrin Saturation (%)

92 (87–97)

83 (75–92)

n.s.

Ferritin (ng/ml)

2694 (2006–3383)

1353 (122–2584)

n.s.

Total Body Iron Stores (g)

9.86 (8.19–11.54)

6.11 (3.21–9.02)

0.030

Total lymphocytes (×10 6 /ml)

1.91 (1.69–2.13)

2.30 (1.92–2.67)

n.s.

Total CD4+ cells(×10 6 /ml)

0.98 (0.84–1.11)

1.09 (0.85–1.32)

n.s.

Total CD8+ cells(×10 6 /ml)

0.35 (0.28–0.42)

0.48 (0.36–0.59)

n.s.

  1. Parameters are expressed as mean (95% confidence intervals) except age, which is expressed as mean ± standard deviation (maximum – minimum values).
  2. Estimation of TBIS was obtained in 27 males and 9 females.
  3. *Statistically significant differences between groups (p) were tested using Student's T test.
Back to article page

BMC Medical Genetics

ISSN: 1471-2350

Contact us