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Table 1 Clinical characteristics of patients from trial ALL-BFM 2000

From: Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and susceptibility to pediatric acute lymphoblastic leukemia in a German study population

 

Patients ALL-BFM 2000 (n = 443)

 

Number of subjects (%)

Gender

 

Male

268 (60.5)

Female

175 (39.5)

Age at diagnosis (years)

 

< 1

-

1-< 6

264 (59.6)

6-< 10

80 (18.1)

≥ 10

99 (22.3)

DNA indexa

 

< 1.16

258 (58.2)

≥ 1.16

48 (10.8)

no result

137 (30.9)

TEL/AML1 pos.

90 (20.3)

neg.

313 (70.7)

unknown

40 (9.0)

BCR/ABL pos.

9 (2.0)

neg.

412 (93.0)

unknown

22 (5.0)

MLL/AF4 pos.

1 (0.2)

neg.

394 (88.9)

unknown

48 (9.9)

Immunophenotype

 

Precursor B

344 (77.7)

T

81 (18.3)

Bipenotypic

4 (0.9)

Unknown

14 (3.2)

  1. aRatio of DNA content of leukemic G0/G1 cells to normal diploid lymphocytes.
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BMC Medical Genetics

ISSN: 1471-2350

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