Table 5 Comparison of the allelic frequencies of GJB2 sequence variations in unrelated french patients with NSHL and in the general population
patients (n = 318) | general population | ||||
|---|---|---|---|---|---|
GJB2 Sequences variations | Number of unrelated chromosomes | Significance (p-values) | |||
35delG | 38 | 11.9 % | 96/12586 | 0.76 % | S (p < 10-6) |
M34T | 5 | 1.6 % | 81/7034 | 1.15 % | NS (p = 0.66) |
R127H | 3 | 0.94 % | 7/1056 | 0.66 % | NS (p = 0.89) |
V37I | 3 | 0.94 % | 30/7034 | 0.43 % | NS (p= 0.36) |