From: The impact of population heterogeneity on risk estimation in genetic counseling
 |  | AB NE(c) | AB E(d) | BB NE | |||
---|---|---|---|---|---|---|---|
rAB,NE (a) | rAA,E (b) | Relative risk | RMSE | Relative risk | RMSE | Relative risk | RMSE |
0.2 | 0.2 | 0.0030 | 0.0194 | 0.0005 | 0.0419 | 0.0086 | 0.0174 |
 | 0.4 | 0.0096 | 0.0221 | -0.0049 | 0.0431 | 0.0072 | 0.0174 |
 | 0.6 | 0.0117 | 0.0261 | -0.0133 | 0.0451 | 0.0250 | 0.0177 |
 | 0.8 | 0.0197 | 0.0313 | -0.0123 | 0.0460 | 0.0238 | 0.0165 |
0.6 | 0.2 | -0.0052 | 0.0193 | -0.0120 | 0.0444 | 0.0127 | 0.0166 |
 | 0.4 | 0.0141 | 0.0231 | -0.0087 | 0.0464 | 0.0171 | 0.0171 |
 | 0.6 | 0.0179 | 0.0262 | -0.0080 | 0.0460 | 0.0052 | 0.0172 |
 | 0.8 | 0.0285 | 0.0329 | -0.0075 | 0.0457 | 0.0319 | 0.0172 |
 |  | BB E | AA NE | AA E | |||
rAB,NE | rAB,E | Relative risk | RMSE | Relative risk | RMSE | Relative risk | RMSE |
0.2 | 0.2 | 0.0051 | 0.0377 | -0.0013 | 0.0388 | -0.0067 | 0.0698 |
 | 0.4 | -0.0076 | 0.0364 | -0.0013 | 0.0401 | -0.0121 | 0.0728 |
 | 0.6 | 0.0060 | 0.0369 | -0.0011 | 0.0397 | -0.0144 | 0.0757 |
 | 0.8 | 0.0171 | 0.0382 | 0.0012 | 0.0409 | -0.0096 | 0.0789 |
0.6 | 0.2 | 0.0093 | 0.0385 | -0.0041 | 0.0401 | -0.0133 | 0.0831 |
 | 0.4 | -0.0009 | 0.0377 | -0.0006 | 0.0402 | -0.0166 | 0.0860 |
 | 0.6 | -0.0081 | 0.0390 | 0.0028 | 0.0403 | -0.0113 | 0.0896 |
 | 0.8 | 0.0262 | 0.0399 | -0.0007 | 0.0393 | -0.0098 | 0.0916 |