A case of autism with an interstitial deletion on 4q leading to hemizygosity for genes encoding for glutamine and glycine neurotransmitter receptor sub-units (AMPA 2, GLRA3, GLRB) and neuropeptide receptors NPY1R, NPY5R

Table 3 Genotyping of markers on chromosome 4q.

Marker	Father Size (bp)¹	Mother Size (bp)	Subject Size (bp)	Distance in Kb²	Conclusion
Pdgfc106	148	150	148		Heterozygous
	150		150
612J15	119	121	123		Deletion
		123
D4S1629	146	146	150	158,914	Deletion
		150
D4S2411	213	209	209	160,016	Deletion
	218
D4S2982	186	179	179	161,672	Deletion
	194	198
D4S2368	322	314	314	169,412	Deletion
		318
D4S3028	234	224	227	177,286	Deletion
		227
M6-91472	151	151	151		Heterozygous
		153	153
D4S2427	300	296	296	178,449	Heterozygous
		300	300
D4S1552	193	183	193	179,526	Heterozygous
		195	195
D4S2924	230	234	230	187,148	Heterozygous
	232	236	236

¹ basepairs ²Kilobases Map position of polymorphic markers in NCBI as of 1/19/04

ISSN: 1471-2350