Genetic study of common variants at the Apo E, Apo AI, Apo CIII, Apo B, lipoprotein lipase (LPL) and hepatic lipase (LIPC) genes and coronary artery disease (CAD): variation in LIPC gene associates with clinical outcomes in patients with established CAD

Table 4 Relative risk of clinical outcomes (a second PTCA, myocardial infarction, CABG, cardiovascular death) according to LIPC gene genotypes

LIPC status	CAD subjects with clinical outcomes	CAD subjects without clinical outcomes
	n. (%)	n. (%)	Odds ratio (95% CI)
CC (wild type) carriers	6 (13.4%)	9 (60%)	1
GG + GC carriers	39 (86.6%)	6 (40%)	7.6 (1.01–57.2)*

Odds ratios were adjusted for age, sex, plasma triglycerides, LDL-cholesterol, HDL-cholesterol, smoking habits (yes/no). Triglycerides were also independent predictors of clinical outcomes (OR 1.01 (95% CI: 1.00–1.02), p < 0.04) * p < 0.03

ISSN: 1471-2350