BMC Medical Genetics

Table 2 Power to detect the difference between the genotypic distributions in two populations, assuming a sample of 230 from population 1 (cases) and 400 from population 2 (controls).

From: Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen

P₁	P₂	P₁-P₂	POWER
0.030	0.010	0.020	0.95
	0.009	0.021	0.97
	0.008	0.022	0.99
	0.007	0.023	0.99
0.050	0.025	0.025	0.77
	0.023	0.027	0.85
	0.021	0.029	0.92
	0.020	0.030	0.94
0.100	0.057	0.043	0.78
	0.055	0.045	0.82
	0.050	0.050	0.91
0.200	0.130	0.070	0.74
	0.120	0.080	0.86
	0.110	0.090	0.94
	0.100	0.100	0.98
0.300	0.200	0.100	0.80
	0.190	0.110	0.88
	0.180	0.120	0.94
0.400	0.280	0.120	0.79
	0.270	0.130	0.84
	0.250	0.150	0.94
0.500	0.360	0.140	0.77
	0.350	0.150	0.84
	0.330	0.170	0.93

Note: P1, the proportion of homozygous mutants in population 1; P2, the proportion of homozygous mutants in population 2.

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