From: Frequency of CHEK2*1100delC in New York breast cancer cases and controls
Positive for CHEK2*1100delC (%) | |
---|---|
Controls | |
Jewish (New York) | 3/1096 (0.3%) |
Non-Jewish (New York) | 2/569 (0.4%) |
Total | 5/1665 (0.3%) |
BRCA1/2-negative individuals of mixed ethnicity with breast cancer from families with 3 or more cases of breast cancer | 0/67 (0.0%) |
BRCA1/2 Ashkenazi founder mutation-negative individuals with breast cancer from families with 3 or more cases of breast cancer | 1/33# (3.0%) |
BRCA2-negativei individuals of mixed ethnicity with male breast cancer | 0/16 (0.0%) |
Individuals with bilateral breast cancer of mixed ethnicity unselected for family history | 0/46 (0.0%) |
Individuals with unilateral breast cancer unselected for family history matched for age, ethnicity | 1/46 (2.2%) |
Clinic-ascertained individuals of Ashkenazi Jewish descent with bilateral breast cancer | 1/46 (2.2%) |
Clinic-ascertained individuals of Ashkenazi Jewish descent with unilateral breast cancer matched for age, family history | 0/46 (0.0%) |