An Improved RSP Method to Detect HpaI Polymorphism in the Apolipoprotein C-1 Gene Promoter

BMC Medical Genetics

Table 1 APOC1 Gene Allele Frequency in 92 Human Subjects

	N^a	H1-allele	H2-allele	Total alleles^b
Total	92	130 (0.707)	54 (0.293)	184 (1.000)
White	30	51 (0.823)	11 (0.177)	62 (1.000)
Black	60	78 (0.650)	42 (0.350)	120 (1.000)
P^c			= 0.024

^a In the study group, 53 males, 39 females; 30 white Caucasians, 60 African Americans, 2 are other races whose allele frequencies were not calculated separately. ^b There are 48 people with the H1/H1 genotype: 26 are the black, 21 are the white and 1 is other race; 34 with H1/H2: 26 are the black, 7 are the white and 1 is other race; and 10 with H2/H2: 8 are the black and 2 are the white. The observed heterozygosity was 0.370 (34/92). ^c Black vs White.

ISSN: 1471-2350