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Table 3 Effect of BMI on BP by rs13390641 genotype classes

From: Identification of a genetic variant at 2q12.1 associated with blood pressure in East-Asians by genome-wide scan including gene-environment interactions

Trait

Genotype

n

Beta (se)

P

SBP

GG

8980

0.92 (0.05)

4.62 × 10-66

 

GA

2051

1.32 (0.11)

5.76 × 10-32

 

AA

135

1.58 (0.47)

9.68 × 10-4

DBP

GG

8980

0.75 (0.04)

7.81 × 10-96

 

GA

2051

0.99 (0.07)

2.02 × 10-39

 

AA

135

1.35 (0.31)

3.26 × 10-5

  1. SBP, systolic blood pressure; DBP, diastolic blood pressure; n, sample size of each subgroup; Beta, standardized regression coefficient; se, standard error.
  2. The association analyses between BP and BMI in each group were performed using linear regression adjusted by age and sex.