Table 1 Descriptive statistics of study samples
Traits | Discovery | Replication 1 | Replication 2 | *P | ||
|---|---|---|---|---|---|---|
KARE (n = 7,486) | HEXA (n = 3,703) | Ehime (n = 356) | Amagasaki (n = 485) | |||
Age | 51.4 ± 8.77 | 53.2 ± 8.33 | 61.3 ± 11.2 | 61.6 ± 6.97 | < 0.0001 | |
Gender | male (%) | 3744 (50.0%) | 1651 (44.6%) | 126 (35.4%) | 260 (53.6%) | - |
female (%) | 3742 (50.0%) | 2052 (55.4%) | 230 (64.6%) | 225 (46.3%) | - | |
Blood pressure | SBP (mmHg) | 119.6 ± 17.4 | 121.7 ± 14.4 | 129.2 ± 19.7 | 128.4 ± 20.8 | < 0.0001 |
DBP (mmHg) | 79.3 ± 11.1 | 77.1 ± 9.89 | 74.8 ± 11.0 | 77.2 ± 11.8 | < 0.0001 | |
Anthropometric measures | Height (cm) | 160.5 ± 8.62 | 161.5 ± 8.10 | 158.0 ± 8.52 | 160.1 ± 7.97 | < 0.0001 |
Weight (kg) | 63.0 ± 10.1 | 62.6 ± 9.97 | 56.8 ± 10.6 | 59.5 ± 10.2 | 0.076 | |
BMI (kg/m2) | 24.4 ± 3.07 | 24.0 ± 2.90 | 22.6 ± 2.96 | 23.1 ± 3.13 | < 0.0001 | |
|  | WHR | 0.88 ± 0.07 | 0.86 ± 0.07 | - | - | < 0.0001 |