Table 3 Polymorphisms in TNFAIP3 gene and risks of rheumatoid arthritis stratified by age
Genotype | ≤53 | >53 | ||||
|---|---|---|---|---|---|---|
Cases (%) | Controls (%) | OR [95% CI] | Cases (%) | Controls (%) | OR [95% CI] | |
rs2230926 | Â | Â | Â | Â | Â | Â |
  TT | 452(80.7) | 564(88.3) | 1.00 | 620(86.1) | 569(88.8) | 1.00 |
  TG | 104(18.6) | 75(11.7) | 1.73[1.26-2.39] | 96(13.3) | 68(10.6) | 1.30[0.93-1.80] |
  GG | 4(0.7) | 0(0.0) | — | 4(0.6) | 4(0.6) | 0.92[0.23-3.69] |
  TG/GG | 108(19.3) | 75(11.7) | 1.80[1.31-2.47] | 100(13.9) | 72(12.2) | 1.28[0.92-1.76] |
rs13207033 | Â | Â | Â | Â | Â | Â |
  GG | 472(84.3) | 528(82.6) | 1.00 | 568(78.9) | 520(81.1) | 1.00 |
  GA | 84(15.0) | 107(16.7) | 0.88[0.64-1.20] | 148(20.6) | 109(17.0) | 1.24[0.95-1.64] |
  AA | 4(0.7) | 4(0.6) | 1.12[0.28-4.50] | 4(0.6) | 12(1.9) | 0.31[0.10-0.95] |
  GA/AA | 88(15.7) | 111(17.4) | 0.89[0.65-1.20] | 152(21.1) | 121(18.9) | 1.15[0.88-1.50] |
rs10499194 | Â | Â | Â | Â | Â | Â |
  CC | 499(89.1) | 600(93.9) | 1.00 | 657(91.3) | 615(95.9) | 1.00 |
  CT | 60(10.7) | 38(5.9) | 1.89[1.24-2.90] | 60(8.3) | 25(3.9) | 2.25[1.39-3.63] |
  TT | 1(0.2) | 1(0.2) | 1.20[0.08-19.27] | 3(0.4) | 1(0.2) | 2.81[0.29-27.07] |
  CT/TT | 61(10.9) | 39(6.1) | 1.88[1.24-2.86] | 63(8.7) | 26(4.1) | 2.27[1.42-3.63] |