A whole genome SNP genotyping by DNA microarray and candidate gene association study for kidney stone disease

BMC Medical Genetics

Table 1 Candidate genes and SNPs associated with KSD

Gene	Number of SNP in gene region			SNP with the least P-value	P-value^c
Gene	SNP on microarray	SNP with P < 0.05	SNP with P < 0.005	SNP with the least P-value	P-value^c
S100A12	1	1	0	rs4772	0.04258
BGLAP	1	1	1	rs759330	0.00070
HSPG2	30	3	0	rs16826053	0.01248
IL1R1	19	1	0	rs871657	0.04641
AHSG	3	2	0	rs2070635	0.02556
CLDN16	8	1	0	rs17504970	0.00651
SLC2A9	122	21	1	rs939134	0.00428
SLC26A2	6	1	0	rs245081	0.03632
EDN1	10	2	0	rs2070699	0.02020
EGFR	92	2	2	rs7801956	0.00958
CALCR	54	1	0	rs13232226	0.03644
SLC26A5	33	1	0	rs17142677	0.04889
CAV1	19	2	0	rs6867	0.03657
CD44	52	12	1	rs353647	0.00298
F2	6	1	0	rs2070852	0.01117
VDR	39	4	0	rs2254210	0.01815
RASGRP1	21	7	0	rs7177101	0.00701
ANXA2	23	4	0	rs7183894	0.03945
CDH1	33	1	0	rs12444784	0.04469
HAO1	35	11	4	rs6118004	0.00179
AR	21	1	0	rs5031002^a	0.02756
HPRT1	3	2	0	rs6634993^b	0.04254

^aSNP was significantly different between patients and control subjects only in male group.
^bSNP was significantly different between patients and control subjects only in female group.
^cUncorrected P-value.

ISSN: 1471-2350