Chr | SNP of interest | Alleles | Replacement SNP | Gene | Alleles | Risk Allele | MAF | OR |
---|
1 | rs2651899 | T > C | |
PRMD16
| | C | 0.45 | 1.10 |
1 | rs3790455 | | rs2274316 |
MEF2D
| A > C | C | 0.34 | 1.23 |
2 | rs10166942 | | rs1003540 |
TRMP8
| A > G | A | Na | Na |
3 | rs7640543 | | rs4075749 |
TGFBR2
| T > C | C | Na | Na |
6 | rs9349379 | A > G | |
PHACTR1
| | A | 0.38 | 0.82 |
8 | rs1835740 | C > T | |
MTDH
| | T | 0.22 | 1.0 |
9 | rs6478241 | G > A | |
ASTN2
| | A | 0.38 | 1.22 |
12 | rs11172113 | T > C | |
LRP1
| | T | 0.4 | 0.86 |
-
Chr = chromosome; SNP of interest = SNPs identified in previous GWAS, see article text for references; Replacement SNP = SNPs of interest not genotyped on the Illumina chip were replaced with other genotyped SNPs in linkage disequilibrium with the SNP of interest (r
2 > 0.89); Gene = the SNPs are either located within or close to these genes; MAF = minor allele frequency from Freilinger et al. [14]; OR = odds ratio from Freilinger et al. [14].