Table 2 Most obviously dysregulated genes sorted by P value in liver metastatic uveal melanoma compare to non-metastatic tumors
From: Expression analysis of genes and pathways associated with liver metastases of the uveal melanoma
Gene symbol | P value | Mean of intensities: no metastasis | Mean of intensities: metastasis | Fold change |
|---|---|---|---|---|
NEURL1B | 1.67 × 10-9 | 51.47 | 88.42 | 1.72 |
EXT1 | 2.82 × 10-9 | 203.15 | 362.35 | 1.78 |
DERL1 | 4.89 × 10-9 | 178.31 | 412.54 | 2.31 |
GALNTL4 | 1.22 × 10-8 | 57.44 | 128.49 | 2.24 |
MR1 | 1.41 × 10-8 | 60.08 | 98.74 | 1.64 |
DDX39 | 3.31 × 10-8 | 347.31 | 556.46 | 1.60 |
HTR2B | 3.49 × 10-8 | 41.04 | 574.49 | 14.00 |
RAB2A | 5.29 × 10-8 | 363.13 | 741.99 | 2.04 |
C10orf26 | 6.68 × 10-8 | 376.40 | 569.30 | 1.51 |
GJC1 | 7.39 × 10-8 | 25.95 | 75.05 | 2.89 |
CHL1 | 8.99 × 10-8 | 80.84 | 17.12 | 0.21 |
ZNF33B | 2.17 × 10-8 | 41.91 | 21.24 | 0.51 |
OVOS2 | 2.44 × 10-8 | 857.96 | 185.87 | 0.22 |
EIF1B | 3.35 × 10-7 | 1008.84 | 567.87 | 0.56 |
PHLDA1 | 5.22 × 10-7 | 370.24 | 134.93 | 0.36 |
PLSCR4 | 5.34 × 10-7 | 114.83 | 53.41 | 0.47 |
MEGF10 | 8.38 × 10-7 | 165.39 | 26.05 | 0.16 |
ZNF415 | 1.19 × 10-6 | 37.03 | 13.91 | 0.38 |
ZNF667 | 1.25 × 10-6 | 34.08 | 16.02 | 0.47 |
MEGF10 | 1.66 × 10-6 | 22.24 | 10.21 | 0.46 |