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Table 4 Multivariate logistic regression modeling of association between 1-carbon enzyme alleles and CT gene expression

From: Cancer-testis gene expression is associated with the methylenetetrahydrofolate reductase 677 C>T polymorphism in non-small cell lung carcinoma

Polymorphism

OR $

95% CI

P*

MTHFR 677 (rs1801133)

13.18

1.96-88.5

0.004

MTHFR 1298 (rs1801131)

0.56

0.15-2.09

0.53

MTR 2756 (rs1805087)

0.81

0.14-4.75

1

MTRR 66 (rs1801394)

0.67

0.22-2.00

0.52

RFC 80 (rs1051266)

0.7

0.24-2.07

0.62

  1. $ Based on number of major alleles, adjusted for age, sex, histology and t stage; * computed using the EXACT option of PROC LOGISTIC in SAS to account for the small data set.