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Table 3 Multivariate analysis of CT gene expression with MTHFR 677 genotypes

From: Cancer-testis gene expression is associated with the methylenetetrahydrofolate reductase 677 C>T polymorphism in non-small cell lung carcinoma

Parameter

OR

95% CI

P*

MTHFR 677 C>T (rs1801133)

CC

32.33

2.42-431.52

0.003

CT/TT

1**

  

Age$

 

1.03

0.94-1.12

0.69

Sex(female vs. male)

 

0.28‡

0.02-3.86

0.52

Histology

SQCC#

18.46

1.19-284.49

0.04

non-SQCC

1**

  

T Stage

T1

0.31

0.03-3.56

0.53

T2, 3, 4

1**

  
  1. * Computed from a logistic regression model using the EXACT option of PROC LOGISTIC in SAS to account for the small data set; $continuous variable. # SQCC Squamous cell carcinoma; ‡reference = male; **reference group.