Population | N total | Demyelinating/mixed polyneuropathy (CMT1, DSS † , CHN $ ) | Axonal polyneuropathy (CMT2) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | (%) | N | (%) | |||||||||||
PMP22(dup) | MPZ | EGR2 | LITAF | NEFL | PMP22 | GJB1 | MFN2 | NEFL | MPZ | GJB1 | ||||
Spanish [15] | 47 | 35 | excl | 8.6 | - | - | - | 2.9 | 17.1 | 7 | - | - | 0 | 57.1 |
Korean [16] | 57 | 32 | 46,9 | 3.1 | 3.1 | - | 3.1 | 3.1 | 6.2 | 18 | - | 5.6 | 11.1 | 5.6 |
Italian [17] | 172 | 170 | 57.6 | 2.4 | 0 | - | - | 1.2 | 7.1 | 0 | - | - | - | - |
Australian [18] | 224 | 224£ | 60.7 | 3.1 | - | - | - | 1.3 | 12.1 | 0 | - | - | - | - |
Finnish [19] | 58 | 23 | excl | 13.0 | - | - | - | 4.3 | 13.0 | 29 | - | - | 0 | 24.1 |
Japanese [20] | 354 | 227 | 23.3 | 8.8 | 0.4 | 0 | 3.5 | 4.4 | 8.4 | 127 | 11.3 | 0 | 3.9 | 4.7 |
British [21] | 775 | 443 | 28.2 | 4.2 | 3.3 | - | 9.5 | 5.3 | 25.8 | NR | 13.6 | - | 4.6 | 2.7 |
American [6] | 153 | 145 | 51.6 | 3.4 | 0.7 | - | 0 | 3.4 | 5.5* | 7 | - | 14.3 | 0 | 42.9 |
Russian [22] | 174 | 108 | 53.7 | 4.6 | - | - | - | 1.9 | 7.4 | 32 | - | - | 0 | 3.1 |
European [9] | 323 | 26 | - | - | - | - | - | - | - | 249 | 11.2 | - | - | - |
American [8] | 13 | 0 | - | - | - | - | - | - | - | 13 | 23.1 | - | - | - |
American [23] | 39 | 1 | - | - | - | - | - | - | - | 38 | 17,9 | - | - | - |
Average | 2389 | 1407 | 41.8 | 5.0 | 0.5 | 0 | 2.2 | 2.6 | 8.8 | 520 | 12.2 | 1.3 | 3.2 | 10.0 |
This study | 435 | 134 | 18.7‡ | 6.0 | 0 | 0 | 0.7 | 0 | 6.7 | 193 | 5.7 | 0.5 | 1.0 | 1.5 |