Figure 1

Location of the 5 CpG sites analysed within the I.4 promoter region of the aromatase gene. Numbers indicate positions of CpG sites analysed relative to the transcription start site (TSS, +1) of I.4, sites 1- 5n refer to I.4.1 – 5 respectively. Cis-acting elements are shown in circles (5, 14, 37). GAS, interferon γ activation site; GRE, glucocorticoid response element; Runx2, Runt-related transcription factor 2.