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Table 6 Results of regression analyses of OXTR coding variants detected in Iowa case and control mothers

From: Sequence variants in oxytocin pathway genes and preterm birth: a candidate gene association study

(A) Model1 n(case, control) P R2
rs4686302 (A218T) 60, 60 0.19 0.020
rs237902 (N230N) 60, 60 0.24 0.015
rs61740241 (A238T) 60, 59 0.75 0.001
rs4686302 (A218T) + rs237902 (N230N)2 60, 60 0.04, 0.053 0.062
(B) Model 1 n Gestational age Birth weight
P R2 P R2
rs4686302 (A218T) 120 0.14 0.019 0.08 0.025
rs237902 (N230N) 120 0.23 0.022 0.17 0.016
rs61740241 (A238T) 119 0.77 0.001 0.53 0.003
rs237902 (N230N) + rs61740241 (A238T)4 120 0.03, 0.04 0.055 N/A N/A
rs4686302 (A218T) + rs61740241 (A238T)5 120 N/A N/A 0.008, 0.01 0.074
  1. 1(A) Logistic regression analysis to predict case/control status and (B) Linear regression analysis to predict gestational age and birth weight.
  2. 2The most parsimonious model for predicting case/control status.
  3. 3 rs4686302 OR=2.861 (1.041, 7.859) and rs237902 OR=1.803 (0.993, 3.273).
  4. 4The most parsimonious model for predicting gestational age.
  5. 5The most parsimonious model for predicting birth weight.