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Table 3 Allele frequencies (af) of the more common HLA class I and II molecules found in patients with Papillon-Lefèvre Syndrome, their relatives and controls

From: Identification of novel mutation in cathepsin C gene causing Papillon-Lefèvre Syndrome in Mexican patients

Alleles Patients   Relatives   Controls  
  (N = 18)   (N = 30)   (N = 82)  
HLA-A   af   af   af
A*24 6 0.3333 8 0.2667 12 0.1463
A*02 3 0.1667 4 0.1333 24 0.2927
A*33 3 0.1667 2 0.0667 1 0.0122
A*31 2 0.1111 5 0.1667 8 0.0976
A*03 2 0.1111 2 0.0667 2 0.0244
HLA-B       
B*35 6 0.3333 9 0.3000 17 0.2073
B*65 3 0.1667 2 0.0667 2 0.0244
B*44 2 0.1111 2 0.0667 9 0.1098
B*51 1 0.0556 2 0.0667 4 0.0488
B*60 1 0.0556 2 0.0667 3 0.0366
HLA-DRB1       
DRB1*11 6 0.3333 6 0.2000 6 0.0732
DRB1*04 4 0.2222 9 0.3000 20 0.2439
DRB1*01 3 0.1667 6 0.2000 13 0.1585
DRB1*15 3 0.1667 4 0.1333 3 0.0366
DRB1*07 1 0.0556 2 0.0667 8 0.0976
HLA-DQB1       
DQB1*0301 7 0.3889 9 0.3000 20 0.2439
DQB1*0302 4 0.2222 9 0.3000 14 0.1707
DQB1*0501 4 0.2222 4 0.1333 9 0.1098
DQB1*0601 2 0.1111 2 0.0667 8 0.0976
DQB1*0201 1 0.0556 5 0.1667 14 0.1707