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Table 4 Genotypes and odds ratios in age-related macular degeneration (AMD) and normal patients with risk allele, assuming a dominant effect

From: Mitochondrial DNA haplogroups confer differences in risk for age-related macular degeneration: a case control study

  Early AMD Late AMD Total AMD Normal
ARMS2 Homozygous T (risk) 11/60 (18%) 19/101 (19%) 30/161 (19%) 10/164 (6%)
ARMS2 Homozygous G 21/60 (35%) 24/101 (24%) 45/161 (28%) 83/164 (51%)
ARMS2 Heterozygous 28/60 (47%) 58/101 (57%) 86/161 (53%) 71/164 (43%)
OR (p-value) 1.81 (0.07) 3.13 (0.0001) 4.72 (0.00001)  
CFH Homozygous C (risk) 11/55 (20%) 18/94 (19%) 29/97 (20%) 16/163 (9.8%)
CFH Homozygous T 23/55 (42%) 29/94 (31%) 52/97 (35%) 85/163 (52%)
CFH Heterozygous 21/55 (38%) 47/94 (50%) 68/97 (45%) 62/163 (38%)
OR (p-value) 1.27 (0.54) 2.05 (0.014) 1.71 (0.027)  
  1. OR, Odds Ratio.