BMC Medical Genetics

Table 2 Hazard rate ratios (HR) and 95% confidence intervals (95% CI) for the associations between MTTP -164 T/C polymorphism, CVD (combined endpoints), MI and IS

From: Microsomal triglyceride transfer protein -164 T > C gene polymorphism and risk of cardiovascular disease: results from the EPIC-Potsdam case-cohort study

	Cholesterol < 200 mg/dL			Cholesterol ≥ 200 mg/dL
	HR (95% CI)^a			HR (95% CI)^a
	CVD	MI	IS	CVD	MI	IS
Cases, n	139	69	70	185	77	40
C allele	1.38 (1.07-1.78)	1.19 (0.82-1.72)	1.60 (1.16-2.20)	0.77 (0.58-1.03)	0.76 (0.54-1.07)	0.77 (0.48-1.23)
P_additive	0.014	0.353	0.004	0.075	0.113	0.273
Dominant	1.76 (1.22-2.54)	1.41 (0.85-2.33)	2.22 (1.35-3.64)	0.67 (0.48-0.94)	0.65 (0.43-0.97)	0.69 (0.40-1.18)
P_dominant	0.002	0.186	0.002	0.021	0.036	0.172
Recessive	0.73 (0.31-1.69)	0.71 (0.21-2.39)	0.75 (0.25-2.27)	0.98 (0.53-1.82)	0.99 (0.47-2.06)	0.93 (0.33-2.66)
P_recessive	0.458	0.580	0.616	0.948	0.969	0.892

^aAdjusted for age and sex.

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ISSN: 1471-2350

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