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Table 2 The association between BRAP rs11066001 and stroke

From: Lack of association between a functional variant of the BRCA-1 related associated protein (BRAP) gene and ischemic stroke

 

rs11066001 genotype

Recessive effect* (OR, Adjusted p value)

AA

AG

GG

age- and sex-comparable

Plaque-free

All

Stroke

All stroke cases (N = 1074)

571 (54.8%)

388 (37.2%)

83 (8.0%)

1.08, p = 0.70

0.97, p = 0.91

0.94, p = 0.74

Stroke Subtypes

      

 Large artery atherosclerosis (N=247)

132 (54.8%)

93 (38.6%)

16 (6.6%)

1.01, p = 0.98

0.82, p = 0.64

0.81, p = 0.56

 Cardio-embolism (N = 118)

62 (53.9%)

44 (38.3%)

9 (7.8%)

0.85, p = 0.71

0.70, p = 0.48

0.73, p = 0.50

 Small vessels occlusion (N=457)

246 (55.5%)

162 (36.6%)

35 (7.9%)

1.24, p = 0.42

1.05, p = 0.86

1.01, p = 0.97

 Other etiologies (N=252)

131 (53.9%)

89 (36.6%)

23 (9.5%)

1.26, p = 0.43

1.05, p = 0.87

1.09, p = 0.77

Controls

age- and sex-comparable controls (N = 1106)

529 (49.5%)

458 (42.9%)

81 (7.6%)

ref.

--

--

 

Plaque-free controls (N = 1283)

619 (50.4%)

518 (42.2%)

90 (7.3%)

--

ref.

--

 

All controls (N = 1936)

929 (49.8%)

787 (42.2%)

150 (8.0%)

--

--

ref.

  1. Adjusted p value was obtained from logistic regression with adjustment for traditional risk factors (age, sex, diabetes, hypertension, hypercholesterolemia, and smoking).