Table 4 Association between SNPs and hemorrhagic stroke using the additive, dominant, genotype, and the recessive models
From: Association between paraoxonase gene and stroke in the Han Chinese population
SNP | Model | Allele or geno | F_HS | F_Control | T-Statistic | Logistic Regression | ||
|---|---|---|---|---|---|---|---|---|
OR(95% CI) | P unadjusted | OR(95% CI) | P adjusted | |||||
rs854571 | Additive | C > T | 92/316 | 344/982 | 0.76(0.57-1.00) | 5.00E-02 | 0.76(0.57-1.01) | 5.54E-02 |
|  | Dominant | CC + CT/TT | 78/158 | 289/491 | 0.68(0.48-0.98) | 3.68E-02 | 0.70(0.48-1.01) | 5.57E-02 |
|  | Recessive | CC/CT + TT | 14/158 | 55/491 | 0.77(0.42-1.43) | 4.08E-01 | 0.71(0.38-1.34) | 2.95E-01 |
rs13306698 | Additive | A > G | 33/324 | 98/988 | 1.03(0.67-1.59) | 8.85E-01 | 1.06(0.68-1.66) | 7.93E-01 |
|  | Dominant | AA + AG/GG | 33/162 | 96/494 | 1.06(0.68-1.65) | 7.95E-01 | 1.09(0.69-1.72) | 7.06E-01 |
|  | Recessive | AA/AG + GG | 0/162 | 2/494 | 0.00(0.00-inf) | 9.99E-01 | 0.00(0.00-inf) | 9.99E-01 |
rs854572 | Additive | C > G | 151/320 | 413/964 | 1.20(0.93-1.54) | 1.73E-01 | 1.24(0.95-1.61) | 1.20E-01 |
|  | Dominant | CC + CG/GG | 118/160 | 324/482 | 1.37(0.92-2.04) | 1.23E-01 | 1.38(0.91-2.08) | 1.27E-01 |
|  | Recessive | CC/CG + GG | 33/160 | 89/482 | 1.15(0.73-1.79) | 5.46E-01 | 1.25(0.79-1.99) | 3.38E-01 |
rs7493 | Additive | C > G | 64/324 | 176/974 | 1.12(0.81-1.55) | 4.94E-01 | 1.05(0.75-1.46) | 7.77E-01 |
|  | Dominant | CC + CG/GG | 57/162 | 163/487 | 1.08(0.74-1.57) | 6.90E-01 | 1.03(0.70-1.51) | 8.94E-01 |
|  | Recessive | CC/CG + GG | 7/162 | 13/487 | 1.65(0.65-4.20) | 2.97E-01 | 1.28(0.49-3.36) | 6.13E-01 |
rs662 | Additive | G > A | 108/324 | 356/978 | 0.88(0.68-1.14) | 3.36E-01 | 0.85(0.65-1.12) | 2.48E-01 |
|  | Dominant | GG + GA/AA | 88/162 | 282/489 | 0.87(0.61-1.25) | 4.56E-01 | 0.82(0.56-1.18) | 2.85E-01 |
|  | Recessive | GG/GA + AA | 20/162 | 74/489 | 0.79(0.47-1.34) | 3.83E-01 | 0.80(0.46-1.38) | 4.26E-01 |
rs12026 | Additive | C > G | 64/322 | 174/978 | 1.15(0.83-1.59) | 3.95E-01 | 1.10(0.78-1.53) | 5.92E-01 |
|  | Dominant | CC + CG/GG | 57/161 | 162/389 | 1.11(0.76-1.61) | 5.96E-01 | 1.07(0.72-1.57) | 7.44E-01 |
|  | Recessive | CC/CG + GG | 7/161 | 12/489 | 1.81(0.70-4.67) | 2.22E-01 | 1.47(0.55-3.92) | 4.39E-01 |
rs1053275 | Additive | A > G | 58/318 | 186/994 | 0.97(0.71-1.33) | 8.55E-01 | 0.96(0.70-1.33) | 8.07E-01 |
|  | Dominant | AA + AG/GG | 49/159 | 165/497 | 0.90(0.61-1.32) | 5.77E-01 | 0.91(0.61-1.35) | 6.36E-01 |
|  | Recessive | AA/AG + GG | 9/159 | 21/497 | 1.36(0.61-3.03) | 4.53E-01 | 1.17(0.51-2.69) | 7.09E-01 |
rs705381 | Additive | G > A | 32/312 | 151/990 | 0.62(0.41-0.94) | 2.42E-02 | 0.62(0.40-0.95) | 2.90E-02 |
|  | Dominant | GG + GA/AA | 30/156 | 144/395 | 0.58(0.37-0.90) | 1.61E-02 | 0.57(0.36-0.90) | 1.65E-02 |
|  | Recessive | GG/GA + AA | 2/156 | 7/495 | 0.91(0.19-4.40) | 9.02E-01 | 1.22(0.24-6.22) | 8.13E-01 |
rs2074353 | Additive | A > G | 74/340 | 230/982 | 0.99(0.74-1.32) | 9.57E-01 | 0.96(0.72-1.29) | 8.05E-01 |
|  | Dominant | AA + AG/GG | 63/159 | 197/491 | 0.98(0.68-1.41) | 9.11E-01 | 0.98(0.67-1.42) | 8.98E-01 |
|  | Recessive | AA/AG + GG | 11/159 | 33/491 | 1.03(0.51-2.09) | 9.31E-01 | 0.87(0.42-1.82) | 7.21E-01 |
rs854560 | Additive | A > T | 9/324 | 39/996 | 0.70(0.34-1.46) | 3.46E-01 | 0.57(0.26-1.25) | 1.58E-01 |
|  | Dominant | AA + AT/TT | 9/162 | 38/498 | 0.71(0.34-1.51) | 3.74E-01 | 0.57(0.26-1.28) | 1.74E-01 |
|  | Recessive | AA/AT + TT | 0/162 | NA | NA | NA | NA | NA |