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Table 1 Correlation of clinicophthologic variables with MUC2 mRNA in HCC

From: The silence of MUC2 mRNA induced by promoter hypermethylation associated with HBV in Hepatocellular Carcinoma

Variable

 

No.(74)

Mean-Δct (± SE)

Pvalue*

Gender

Male

65

−4.63 (± 0.62)

0.722

 

Female

9

−5.27 (± 1.89)

 

Age(y)

> = 40

59

−5.57 (± 0.67)

< 0.001

 

< 40

15

−1.29 (± 0.80)

 

HBV history

Yes

43

1.07 (± 0.65)

0.393

 

No

31

1.89 (± 0.68)

 

Differentiation

G1

62

−4.61 (± 0.65)

0.733

 

G2-3

12

−5.17 (± 1.44)

 

Cirrhosis

Yes

39

−4.22 (± 0.82)

0.391

 

No

35

−5.24 (± 0.86)

 

Tobacco

Yes

33

−5.04 (± 0.88)

0.609

 

No

41

−4.43 (± 0.80)

 

Alcohol

Yes

14

−4.01 (± 1.32)

0.572

 

No

60

−4.87 (± 0.66)

 

HBV (copy/ml)

> = 105

25

−6.69 (± 1.08)

0.015

 

< 105

49

−3.69 (± 0.67)

 

AFP (μg/l)

> = 30

45

−3.73 (± 0.75)

0.040

 

< 30

29

−6.25 (± 0.94)

 
  1. * Statistical significance determined using the independent samples test.