Table 3 Frequency of NF2-gene mutations in our patients and other series from the literature reporting >10 sporadic meningiomas
Reference | No of mutated cases/total cases (%) | Exons involved |
|---|---|---|
Ruttledge, et al., 1994 [27]** | 24/170 (14%) | 2-7-8-9-10-11-12 |
LeKanne Deprez, et al., 1994 [26]** | 19/48 (40%) | 1-2-3-4-5-6-11-12 |
Merel, et al., 1995 [25]** | 15/57 (26%) | 1-2-3-4-5-6-7-8-9-12-13 |
Wellenreuther, et al., 1995 [24] | 41/70 (59%) | 1-2-3-4-5-6-7-8-10-11-12-13 |
Ng, et al., 1995 [23] | 7/26 (27%) | 4-5-6-7-10 |
Papi, et al., 1995 [22]** | 9/61 (15%) | 2-5-7-8-11 |
Harada, et al., 1996 [21] | 8/23 (35%) | 1-2-5-8-11-12 |
Ruttledge, et al., 1996 [20] | 67/111 (60%) | 1-2-3-4-6-7-8-10-11-12-13-14-15-17 |
De Vitis, et al., 1996 [29] | 37/125 (30%) | 2-3-4-5-6-7-8-11-12-13 |
Stangl, et al., 1997 [18] | 10/12 (83%) | 3-5-6-7-8-11-12 |
Leone, et al., 1999 [17]** | 11/81 (14%) | 2-7-11 |
Ueki, et al., 1999 [16] | 10/50 (20%) | 4-5-7-10-12-13 |
Evans, et al., 2001 [14] | 4/27 (15%) | 3-4-8-13 |
Joachim, et al., 2001 [13]* | 26/61 (43%) | 1-2-3-4-5-6-7-8-10-11-12-13 |
Szijan, et al., 2003 [11] | 5/14 (35%) | 2-3-8-12-13 |
Lomas, et al., 2005 [10]** | 21/88 (24%) | 1-2-3-4-7-11-12-13 |
Hartmann, et al., 2006 [9]# | 21/80 (20%) | 1-2-3-4-5-6-7-8-9-11-12-13-14-15 |
Kim, et al., 2006 [8]** | 20/42 (48%) | 1-2-4-5-7-10-11-12 |
Hansson, et al., 2007 [7]** | 39/100 (39%) | 1-2-3-4-6-7-8-9-10-12-13-14 |
Goutagny, et al., 2010 [6]& | 14/18 (78%) | 2-5-6-7-8-10-11-12-13 |
Tabernero et al. (2013) | 6/20 (30%) | 2-3-5-9-12 |
Total | 414/1284 (32%) | 1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17 |