Table 1 Type 2 diabetes association for the 11 AGPAT6 variants genotyped in type 2 diabetic individuals and control individuals with normal glucose tolerance
AGPAT6variant | N | Minor:major allele | MAF | Odds ratio | P-value | |
|---|---|---|---|---|---|---|
(95% CI) | ||||||
T2D | NGT | |||||
(wildtype/hetero-/homozygous) | (wildtype/hetero-/homozygous) | |||||
rs13252523 | 1428/2304/802 | 1821/2840/1148 | G:A | 0.44 | 0.95 (0.88-1.01) | 0.098 |
rs7357415 | 2779/1555/197 | 3546/1973/293 | T:A | 0.22 | 0.95 (0.87-1.03) | 0.19 |
rs2977860 | 2158/1931/386 | 2827/2419/478 | T:C | 0.30 | 1.03 (0.95-1.1) | 0.49 |
rs11785763 | 3364/1095/94 | 4307/1405/116 | G:A | 0.14 | 0.99 (0.90-1.08) | 0.79 |
rs999188 | 1379/2271/875 | 1802/2817/1169 | T:G | 0.44 | 1.00 (0.94-1.07) | 0.98 |
rs17600159 | 3941/581/13 | 5123/658/16 | G:A | 0.063 | 1.12 (0.98-1.29) | 0.092 |
rs2977845 | 4124/433/12 | 5332/513/15 | G:A | 0.048 | 1.18 (1.01-1.37) | 0.034 |
rs10504041 | 2980/1359/169 | 3738/1814/256 | G:A | 0.19 | 0.91 (0.84-0.99) | 0.030 |
rs12677439 | 2568/1709/271 | 3374/2062/343 | T:C | 0.24 | 1.06 (0.99-1.15) | 0.11 |
rs6988044 | 3993/566/15 | 5028/786/31 | G:A | 0.069 | 0.87 (0.76-0.99) | 0.030 |
rs890220 | 3376/1107/85 | 4188/1468/151 | G:A | 0.15 | 0.88 (0.80-0.96) | 0.0052 |