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Table 3 Replication results; Association results derived from logistic regression between rs4977574 and severity of CAD without T2D in Italian (N=2,343) and Canadian studies (N=950)

From: Assessment of the 9p21.3 locus in severity of coronary artery disease in the presence and absence of type 2 diabetes

  

EO CAD

  

OR (95% CI)

P

3VD vs. (2VD+1VD)

rs4977574

Italian

1.734 (1.142-2.633)

9.77E-03

 

Canadian

1.381 (1.124-1.698)

2.14E-03

1VD vs. (2VD+3VD)

rs4977574

Italian

0.721 (0.542-0.958)

2.42E-02

 

Canadian

0.648 (0.527-0.795)

3.28E-05

  1. Odds ratio (OR) adjusted for age and sex; 05 CI, 95% confidence interval of OR; Boldface P denotes nominal P value significance <0.05; EO, early-onset CAD; 1VD=1-vessel disease; 2VD=2-vessel disease; 3VD=3-vessel disease.
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BMC Medical Genetics

ISSN: 1471-2350

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