From: Genetic and biochemical markers of hydroxyurea therapeutic response in sickle cell anemia
Modulators | Bantu/Benin (+HU) | Bantu/Benin (−HU) | P values* |
---|---|---|---|
n = 06 | n = 04 | ||
Hb F ( % ) | 17.41 ± 3.10 | 6.67 ± 4.37 | 0.0069# |
TBARS (ng/mL) | 1066.26 ± 495.09 | 1815.50 ± 334.80 | 0.0303# |
TEAC (mM) | 2.02 ± 0.16 | 2.08 ± 0.18 | 0.6124 |
GST (U/mL) | 1.49 ± 0.62 | 1.27 ± 0.63 | 0.5925 |
CAT (U/mL) | 2294.01 ± 297.29 | 1842.42 ± 397.81 | 0.0725 |
GSH (μM) | 0.62 ± 0.37 | 0.84 ± 0.62 | 0.4981 |