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Table 4 Influence of Bantu and Benin haplotypes on SCA phenotypic expression

From: Genetic and biochemical markers of hydroxyurea therapeutic response in sickle cell anemia

Modulators

Bantu/Bantu (−HU)

Bantu/Benin (−HU)

P values*

n = 06

n = 04

Hb F ( % )

6.78 ± 3.60

6.67 ± 6.37

0.9731

TBARS (ng/mL)

2284.33 ± 435.50

1815.50 ± 334.80

0.1074

TEAC (mM)

1.92 ± 0.13

2.08 ± 0.18

0.1465

GST (U/mL)

2.03 ± 1.02

1.27 ± 0.63

0.2245

CAT (U/mL)

1656.10 ± 413.96

1842.42 ± 397.81

0.4993

GSH (μM)

0.77 ± 0.37

0.84 ± 0.62

0.8317

  1. (−HU) patients not treated with HU. Mean ± standard deviation.
  2. * Comparisons were made by Mann–Whitney test.