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Table 1 Characteristics of the subjects and frequency of genotypes

From: Influence of IL17A polymorphisms on the aberrant methylation of DAPK and CDH1 in non-cancerous gastric mucosa

 

Total

non CIHM

CIHM

p value*

number of subjects

401

153

248

 

mean age ± SD

60.0 ± 13.8

60.2 ± 13.7

59.9 ± 13.9

NS

male : female

230 : 171

87 : 66

143 : 105

NS

H. pylori positive rate

241/401

71/153

170/248

<0.0001

-197 G > A

    

GG

155

65

90

 

GA

204

74

130

 

AA

41

14

27

 

(unknown)

1

0

1

 

A allele frequency

35.8%

33.3%

37.2%

NS

*1249 C > T

    

CC

340

124

216

0.058a

CT

42

20

22

 

TT

16

9

7

 

(unknown)

3

0

3

 

T allele frequency

9.3%

12.4%

7.3%

0.023

  1. non CIHM: neither DAPK nor CDH1 were methylated.
  2. CIHM: both or either DAPK or CDH1was methyaled.
  3. *: unmethylated vs. methylated.
  4. a: frequency of *1249 CC genotype.