Figure 2

Linkage disequilibrium (LD) plots for African ancestry (AA) trauma subjects for 4 genes with positive ALI associations. Previously reported ALI-associated SNPs are circled in red, whereas the haplotype block detected to be ALI – associated by one or more kernel function is outlined in yellow. The grayscale reflects the pairwise LD as measured by r², with high LD in black and low/absent LD in white. The ALI – associated genes are (A) IL6, (B) IL10, (C) VEGFA, and (D) IRAK3.