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Table 5 The association of HLA-DRB1*04 alleles with clinical and pathological parameters of primary IgAN patients

From: The genetic variants at the HLA-DRB1 gene are associated with primary IgA nephropathy in Han Chinese

  

HLA-DRB1*04

P

OR

95% CI

Gender

(n = 1104)

Female

0.133 (143)

0.850

1.015

0.809-1.146

Male

0.130 (157)

   

SCr (umol/L)

(n = 1079)

≤120

0.136 (229)

0.705

1.051

0.830-1.331

>120

0.129 (62)

   

Hematuria

(n = 1061)

No

0.125 (19)

0.806

0.994

0.961–1.028

Yes

0.135 (266)

   

Upro (g/24Hr) (n = 1056)

≤3.5

0.138 (233)

0.875

1.025

0.798–1.316

>3.5

0.134 (57)

   

Blood pressure (n = 1076)

Normal

0.143 (171)

0.228

1.095

0.946–1.267

Hypertension

0.125 (120)

   

eGFR, ml/min/1.73 m2 (n = 1079)

≤60

0.130 (241)

0.784

0.964

0.711–1.307

>60

0.135 (41)

   

Glomeruloscerosis (n = 1079)

No

0.124 (201)

0.120

0.844

0.691–1.032

Yes

0.151 (81)

   
  1. OR, odds ratio; CI, confidence interval.