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Table 4 A comparison of the frequencies of HLA-DRB1*04 subtypes in primary IgAN patients and healthy controls of Han Chinese descent

From: The genetic variants at the HLA-DRB1 gene are associated with primary IgA nephropathy in Han Chinese

HLA-DRB1 alleles

Case (n = 935 × 2)

Controls

(n = 2088 × 2)

P

OR

95% CI

DRB1*0401

0.011 (21)

0.0010 (43)

0.786

1.028

0.866–1.221

DRB1*0402

0.003 (5)

0.002 (8)

0.556

1.123

0.730–1.726

DRB1*0403

0.029 (54)

0.014 (60)

2.088 × 10-4

1.318

1.107–1.570

DRB1*0404

0.005 (10)

0.007 (28)

0.601

0.937

0.774–1.134

DRB1*0405

0.067 (125)

0.037 (153)

5.225 × 10-7

1.267

1.138–1.411

DRB1*0406

0.026 (49)

0.021 (89)

0.263

1.073

0.947–1.215

DRB1*0407

0.004 (7)

0.002 (9)

0.284

1.229

0.797–1.893

DRB1*0408

0.002 (3)

0.002 (8)

1.000

0.950

0.661–1.364

DRB1*0409

0

0.009 (4)

0.318

-

-

DRB1*0410

0.006 (11)

0.002 (9)

0.027

1.537

0.946–2.495

DRB1*0411

0.010 (3)

0

0.030

-

-

DRB1*0419

0.001 (2)

0

0.096

0.416

0.381–0.455

DRB1*0420

0.0005(1)

0.0002(1)

0.523

1.382

0.345–5.525

  1. OR, odds ratio; CI, confidence interval.