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Figure 3 | BMC Medical Genetics

Figure 3

From: Mutations in LRP5 cause primary osteoporosis without features of OI by reducing Wnt signaling activity

Figure 3

Luciferase activity in CHO cells transfected with WT-LRP5 or mutant LRP5 in the presence of Wnt3a-CM (white bars) or L1 control medium (grey bars). The activities of the signaling pathway are presented in relative luciferase units (RLU) determined by the ratio between the luciferase and β-galactosidase activities and given as a fold change relative to corresponding samples treated with 10% FBS-DMEM. * p < 0.05, **p < 0.01 as compared with WT-LRP5. Results are expressed as mean ± SD.

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BMC Medical Genetics

ISSN: 1471-2350

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