SNP ID | with GO | w/o GO | Pvaluea | OR (95% CI) |
---|---|---|---|---|
N (%) | N (%) | |||
rs3806933 | ||||
Female | ||||
C/C | 64 (42.7) | 119 (53.1) | 1 | |
C/T | 77 (51.3) | 80 (35.7) | 1.79 (1.16, 2.77) | |
T/T | 9 (6) | 25 (11.2) | 0.007 (genotype) | 0.67 (0.29, 1.52) |
C/T + T/T | 86 (57.3) | 105 (46.9) | 0.047 (dominant) | 1.52 (1.00, 2.31) |
C allele | 205 (68.3) | 318 (71.0) | 1 | |
T allele | 95 (31.7) | 130 (29.0) | 0.44 | 1.13 (0.83, 1.56) |
Male | ||||
C/C | 19 (37.3) | 21 (46.7) | 1 | |
C/T | 24 (47.1) | 22 (48.9) | 1.21 (0.52, 2.82) | |
T/T | 8 (15.7) | 2 (4.4) | 0.18 (genotype) | 4.42 (0.83, 23.47) |
C/T + T/T | 32 (62.7) | 24 (53.3) | 0.35 (dominant) | 1.47 (0.65, 3.33) |
C allele | 62 (60.8) | 64 (71.1) | 1 | |
T allele | 40 (39.2) | 26 (28.9) | 0.13 | 1.59 (0.87, 2.91) |
rs2289276 | ||||
Female | ||||
T/T | 2 (1.3) | 15 (6.7) | 1 | |
C/T | 60 (40.0) | 75 (33.5) | 6.00 (1.32, 27.27) | |
C/C | 88 (58.7) | 134 (59.8) | 0.034 (genotype) | 4.93 (1.10, 22.07) |
C/T + C/C | 148 (98.7) | 209 (93.3) | 0.015 (recessive) | 5.31 (1.20, 23.57) |
C allele | 236 (78.7) | 343 (76.6) | 1 | |
T allele | 64 (21.3) | 105 (23.4) | 0.50 | 0.89 (0.62, 1.26) |
Male | ||||
T/T | 3 (5.9) | 4 (8.9) | 1 | |
C/T | 17 (33.3) | 15 (33.3) | 1.51 (0.29, 7.87) | |
C/C | 31 (60.8) | 26 (57.8) | 0.847 (genotype) | 1.59 (0.33, 7.76) |
C/T + C/C | 48 (94.1) | 41 (91.1) | 0.572 (recessive) | 1.56 (0.33, 7.38) |
C allele | 79 (77.5) | 67 (74.4) | 1 | |
T allele | 23 (22.5) | 23 (25.6) | 0.63 | 0.85 (0.44, 1.65) |
rs2289278 | ||||
Female | ||||
C/C | 80 (53.3) | 148 (66.1) | 1 | |
C/G | 59 (39.3) | 66 (29.5) | 1.65 (1.06, 2.58) | |
G/G | 11 (7.3) | 10 (4.5) | 0.042 (genotype) | 2.04 (0.83, 5.00) |
C/G + G/G | 70 (46.7) | 76 (33.9) | 0.013 (dominant) | 1.70 (1.12, 2.60) |
C allele | 219 (73.0) | 362 (80.8) | 1 | |
G allele | 81 (27.0) | 86 (19.2) | 0.012 | 1.56 (1.10, 2.20) |
Male | ||||
C/C | 34 (66.7) | 29 (64.4) | 1 | |
C/G | 14 (27.5) | 13 (28.9) | 0.92 (0.37, 2.27) | |
G/G | 3 (5.9) | 3 (6.7) | 0.971 (genotype) | 0.85 (0.16, 4.55) |
C/G + G/G | 17 (33.3) | 16 (35.6) | 0.819 (dominant) | 0.91 (0.39, 2.11) |
C allele | 82 (80.4) | 71 (78.9) | 1 | |
G allele | 20 (19.6) | 19 (21.1) | 0.80 | 0.91 (0.45, 1.84) |