SNP ID | GD with GO (201) | GD without GO (269) | GD (470) | Control (78) | P a | P b | OR (95% CI) |
---|---|---|---|---|---|---|---|
N (%) | N (%) | N (%) | N (%) | ||||
Genotype | |||||||
rs3806933 | |||||||
C/C | 83(41.3) | 140 (52.0) | 223 (47.4) | 37 (47.4) | 1 | ||
C/T | 101 (50.2) | 102 (37.9) | 203 (43.2) | 31 (39.7) | 1.67 (1.13, 2.46) | ||
T/T | 17 (8.5) | 27 (10.0) | 44 (9.4) | 10 (12.9) | 0.028 (genotype) | 0.61 | 1.06 (0.55, 2.06) |
C/T + T/T | 118 (58.7) | 129 (48.0) | 247 (52.6) | 41 (52.6) | 0.021 (dominant) | 1 | 1.54 (1.07, 2.23) |
rs2289276 | |||||||
C/C | 5 (2.5) | 19 (7.1) | 24 (5.1) | 9 (11.5) | 1 | ||
C/T | 77 (38.3) | 90 (33.5) | 167 (35.5) | 29 (37.2) | 3.25 (1.16, 9.12) | ||
T/T | 119 (59.2) | 160 (59.5) | 279 (59.4) | 40 (51.3) | 0.065 (genotype) | 0.067 | 2.83 (1.03, 7.79) |
C/T + C/C | 196 (97.5) | 250 (92.9) | 446 (94.9) | 69 (88.5) | 0.026 (recessive) | 0.027 | 2.98 (1.09, 8.12) |
rs2289278 | |||||||
C/C | 114 (56.7) | 177 (65.8) | 291 (61.9) | 41 (52.6) | 1 | ||
C/G | 73 (36.3) | 79 (29.4) | 152 (32.3) | 32 (41.0) | 1.43 (0.97, 2.13) | ||
G/G | 14 (14) | 13 (4.8) | 27 (5.8) | 5 (6.4) | 0.125 (genotype) | 0.29 | 1.67 (0.76, 3.69) |
C/G + G/G | 87 (50.3) | 92 (34.2) | 179 (38.1) | 37 (47.4) | 0.045 (dominant) | 0.12 | 1.47 (1.01, 2.14) |
Allele | |||||||
rs3806933 | |||||||
C allele | 267 (66.4) | 382(71.0) | 649 (69) | 105 (67.3) | 1 | ||
T allele | 135 (33.6) | 156 (29.0) | 291 (31) | 51 (32.7) | 0.13 | 0.66 | 1.24 (0.94, 1.64) |
rs2289276 | |||||||
T allele | 315 (78.4) | 410 (76.2) | 725 (77.1) | 109 (69.9) | 1 | ||
C allele | 87 (21.6) | 128 (23.8) | 215 (22.9) | 47 (30.1) | 0.44 | 0.05 | 0.88 (0.65, 1.21) |
rs2289278 | |||||||
C allele | 301 (74.9) | 433 (80.5) | 734 (78.1) | 114 (73.1) | 1 | ||
G allele | 101 (25.1) | 105 (19.5) | 206 (21.9) | 42 (26.9) | 0.04 | 0.17 | 1.38 (1.01, 1.89) |