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Table 2 Univariate analysis comparing annual decline in FEV1 and clinical variables

From: An interaction between Nrf2 polymorphisms and smoking status affects annual decline in FEV1: a longitudinal retrospective cohort study

Variables

Correlation coefficienta

Annual decline in FEV1

Mean ± SD (mL/yr)

P value

Categorical variables

   

   Gender

  

0.205

Male

 

25.0 ± 28.2

 

Female

 

22.8 ± 24.5

 

   Smoking habits

  

0.005

Never-smokers

 

21.7 ± 24.5

 

Ex-smokers

 

26.7 ± 27.6

 

Current-smokers

 

28.5 ± .30.5*

 

   Smoking indexb

  

0.006

0

 

21.7 ± 24.5

 

0-200

 

28.2 ± 29.6

 

> 200

 

27.0 ± 28.3*

 

Continuous variables

   

   Age

0.105

 

0.001

   BMI

0.038

 

0.245

   FVC (L)

-0.069

 

0.037

   FVC % predicted (%)

-0.146

 

< 0.001

   FEV1 (L)

-0.144

 

< 0.001

   FEV1 % predicted (%)

-0.263

 

< 0.001

   FEV1/FVC (%)

-0.278

 

< 0.001

   Serum IgE (Log IU/mL)

0.097

 

0.003

  1. a Pearson coefficient.
  2. b Smoking index was calculated for current and past smokers by multiplying smoking dose (cigarettes per day) and duration (years smoked).
  3. * p < 0.05 compared with never-smokes (smoking index 0) after Bonferroni post hoc correction.